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High-intensity interval training combined with saffron supplementation modulates stress-inflammatory markers in obese women with type 2 diabetes | ||
| پژوهش در تغذیه ورزشی | ||
| مقاله 6، دوره 1، شماره 1، خرداد 1401، صفحه 55-61 اصل مقاله (591.28 K) | ||
| نوع مقاله: مقاله اصیل | ||
| شناسه دیجیتال (DOI): 10.34785/J019.2022.002 | ||
| نویسندگان | ||
| شادی گلپسندی1؛ سیامند عبدالله پور2؛ هادی گل پسندی* 3 | ||
| 1دانشجوی دکتری فیزیولوژی پزشکی، گروه فیزیولوژی پزشکی، دانشکده پزشکی، دانشگاه کانکوک، سئول، کره جنوبی. | ||
| 2کارشناسی ارشد فیزیولوژی ورزشی، گروه فیزیولوژی ورزشی، دانشکده تربیت بدنی و علوم ورزشی، دانشگاه گیلان، رشت، ایران. | ||
| 3دانشجوی دکتری فیزیولوژی ورزشی، گروه فیزیولوزی ورزشی، دانشکده علوم انسانی و اجتماعی، دانشگاه کردستان، سنندج، ایران | ||
| چکیده | ||
| Introduction: The aim of this study was to investigate the interactive effects of saffron extract supplementation with high-intensity interval training (HIIT) on serum levels of stress-inflammatory markers in obese women with type 2 diabetes. Method: Thirty-two obese women with type 2 diabetes were randomly divided into 4 intervention groups: supplement, HIIT +Supplement, placebo and placebo+ HIIT. The anthropometric and blood characteristics of subjects were evaluated in pre-test and post-test. The method of supplementation was that the supplement group received 100 mg of saffron extract daily. The subjects in the training group also did running on the treadmill in 4 bouts with intensity of 85 to 95% of the maximum heart rate along with 4 periods of active rest at the intensity of 50 to 60% of the maximum heart rate. Results: Data analysis showed that the effect of time was a significant decrease in serum levels of IL-6, NT-proBNP and GDF-15 in the supplement, supplement+ HIIT and placebo+ HIIT groups (P≤0.05). The results of time × group interaction also showed a significant difference between the groups (P≤0.05). So that the decrease in the levels of stress-inflammatory markers in the supplement+ HIIT group had a greater decrease. Conclusion: According to the results, it can be reported that HIIT and saffron supplementation (combination of both) probably reduces the levels of stress-inflammatory markers such as GDF-15, NT-proBNP and IL-6 by reducing fat mass, as well as also improve glucose metabolism and insulin resistance in obese women with diabetes. | ||
| کلیدواژه‌ها | ||
| Growth differentiation factor-15؛ interleukin-6؛ NT-proBNP؛ inflammation؛ type 2 diabetes | ||
| مراجع | ||
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آمار تعداد مشاهده مقاله: 1,299 تعداد دریافت فایل اصل مقاله: 287 |
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