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Golpasandi, Shadi, Khosravi, Mobina, Golpasandi, Hadi. (1403). Investigation of the Levels of Some Antioxidant and Inflammatory Markers Following Supplementation of CoenzymeQ10 after Acute Bouts of Exhausting Aerobic Exercise in Male Judo Athletes. , 2(4), 66-59. doi: 10.22034/ren.2024.142662.1067
Shadi Golpasandi; Mobina Khosravi; Hadi Golpasandi. "Investigation of the Levels of Some Antioxidant and Inflammatory Markers Following Supplementation of CoenzymeQ10 after Acute Bouts of Exhausting Aerobic Exercise in Male Judo Athletes". , 2, 4, 1403, 66-59. doi: 10.22034/ren.2024.142662.1067
Golpasandi, Shadi, Khosravi, Mobina, Golpasandi, Hadi. (1403). 'Investigation of the Levels of Some Antioxidant and Inflammatory Markers Following Supplementation of CoenzymeQ10 after Acute Bouts of Exhausting Aerobic Exercise in Male Judo Athletes', , 2(4), pp. 66-59. doi: 10.22034/ren.2024.142662.1067
Golpasandi, Shadi, Khosravi, Mobina, Golpasandi, Hadi. Investigation of the Levels of Some Antioxidant and Inflammatory Markers Following Supplementation of CoenzymeQ10 after Acute Bouts of Exhausting Aerobic Exercise in Male Judo Athletes. , 1403; 2(4): 66-59. doi: 10.22034/ren.2024.142662.1067

Investigation of the Levels of Some Antioxidant and Inflammatory Markers Following Supplementation of CoenzymeQ10 after Acute Bouts of Exhausting Aerobic Exercise in Male Judo Athletes

Research in Exercise Nutrition
مقاله 6، دوره 2، شماره 4، فروردین 2023، صفحه 66-59    اصل مقاله (1.01 M)
نوع مقاله: Research Paper I Open Access I Released under (CC BY-NC 4.0) license
شناسه دیجیتال (DOI): 10.22034/ren.2024.142662.1067
نویسندگان
Shadi Golpasandi1؛ Mobina Khosravi2؛ Hadi Golpasandi* 3
1PhD student in Exercise Physiology, Department of Kinesiology and Sport Management, Texas A&M University, Texas, USA.
2Masters student, Department of Exercise Physiology, Faculty of Humanities and Social Sciences, University of Kurdistan, Sanandaj, Iran.
3Postdoctoral researcher, Department of Exercise Physiology, Faculty of Humanities and Social Sciences, University of Kurdistan, Sanandaj, Iran.
چکیده
Aim: This study aimed to investigate the effects of short-term supplementation with coenzyme Q10 (CoQ10) on markers of oxidative stress and inflammation, specifically superoxide dismutase (SOD), malondialdehyde (MDA), and interleukin-6 (IL-6), following exhaustive aerobic exercise in judo athletes.

Method: Sixteen male judo athletes participated in a randomized, double-blind, crossover study in which they received CoQ10 or placebo. Participants received CoQ10 supplementation for 30 days after completing a first bout of exhaustive aerobic exercise, then completed a second bout of exhaustive exercise. Blood samples were collected before exercise, immediately, and 24 hours after exercise during the two bouts to measure levels of SOD, MDA, and IL-6. These markers were analyzed using enzyme-linked immunosorbent assay (ELISA) and spectrophotometric techniques.

Results: CoQ10 supplementation significantly increased SOD levels after 30 days of supplementation compared to the placebo group (p<0.05). MDA and IL-6 levels were significantly reduced during the recovery period after CoQ10 supplementation (p<0.05). These findings suggest that CoQ10 effectively enhances antioxidant defences and reduces lipid peroxidation and inflammation induced by exhaustive aerobic exercise.

Conclusion: CoQ10 supplementation improves oxidative stress and inflammatory responses in judo athletes after exhaustive aerobic exercise. CoQ10 may be an effective nutritional strategy to enhance recovery and reduce exercise-induced cellular damage in high-intensity sports

تازه های تحقیق

 

کلیدواژه‌ها
Coenzyme Q10؛ oxidative stress؛ exhausting aerobic exercise؛ judo
اصل مقاله

 

مراجع
  1. 1. Arenas‐Jal M, Suñé‐Negre J, García‐Montoya E. Coenzyme Q10 supplementation: Efficacy, safety, and formulation challenges. Comprehensive reviews in food science and food safety. 2020;19(2):574-94.
  2. 2. Rossi C, Roklicer R, Tubic T, Bianco A, Gentile A, Manojlovic M, et al. The role of psychological factors in judo: a systematic review. International journal of environmental research and public health. 2022;19(4):2093.
  3. 3. Laskowski R, Ziemann E, Olek R, Zembron-Lacny A. The effect of three days of judo training sessions on the inflammatory response and oxidative stress markers. Journal of Human Kinetics. 2011;30(2011):65-73.
  4. 4. Gaweł S, Wardas M, Niedworok E, Wardas P. Malondialdehyde (MDA) as a lipid peroxidation marker. Wiadomosci lekarskie (Warsaw, Poland: 1960). 2004;57(9-10):453-5.
  5. 5. Stephenie S, Chang YP, Gnanasekaran A, Esa NM, Gnanaraj C. An insight on superoxide dismutase (SOD) from plants for mammalian health enhancement. Journal of Functional Foods. 2020;68:103917.
  6. 6. Huang B, Lang X, Li X. The role of IL-6/JAK2/STAT3 signaling pathway in cancers. Frontiers in oncology. 2022;12:1023177.
  7. 7. Sifuentes-Franco S, Sánchez-Macías DC, Carrillo-Ibarra S, Rivera-Valdés JJ, Zuñiga LY, Sánchez-López VA, editors. Antioxidant and anti-inflammatory effects of coenzyme Q10 supplementation on infectious diseases. Healthcare; 2022: MDPI.
  8. 8. Sangsefidi ZS, Yaghoubi F, Hajiahmadi S, Hosseinzadeh M. The effect of coenzyme Q10 supplementation on oxidative stress: A systematic review and meta‐analysis of randomized controlled clinical trials. Food science & nutrition. 2020;8(4):1766-76.
  9. 9. Hou S, Tian Z, Zhao D, Liang Y, Dai S, Ji Q, et al. Efficacy and Optimal Dose of Coenzyme Q10 Supplementation on Inflammation‐Related Biomarkers: A GRADE‐Assessed Systematic Review and Updated Meta‐Analysis of Randomized Controlled Trials. Molecular Nutrition & Food Research. 2023;67(13):2200800.
  10. 10. Gutierrez-Mariscal FM, Arenas-de Larriva AP, Limia-Perez L, Romero-Cabrera JL, Yubero-Serrano EM, López-Miranda J. Coenzyme Q10 supplementation for the reduction of oxidative stress: Clinical implications in the treatment of chronic diseases. International journal of molecular sciences. 2020;21(21):7870.
  11. 11. Shimizu K, Kon M, Tanimura Y, Hanaoka Y, Kimura F, Akama T, Kono I. Coenzyme Q10 supplementation downregulates the increase of monocytes expressing toll-like receptor 4 in response to 6-day intensive training in kendo athletes. Applied Physiology, Nutrition, and Metabolism. 2015;40(6):575-81.
  12. 12. Nikbakht H, Shokouhyar S, Ghazalian F. The effects of coenzyme Q10 supplementation on footsal competition-induced changes in immune system in male players. Eur J Exp Biol. 2013;3(3):370-5.
  13. 13. Yavuz HU, Turnagol H, Demirel AH. Pre-exercise arginine supplementation increases time to exhaustion in elite male wrestlers. Biology of sport. 2014;31(3):187-91.
  14. 14. Moreno-Fernandez J, Puche-Juarez M, Toledano JM, Chirosa I, Chirosa LJ, Pulido-Moran M, et al. Ubiquinol Short-Term Supplementation Prior to Strenuous Exercise Improves Physical Performance and Diminishes Muscle Damage. Antioxidants. 2023;12(6):1193.
  15. 15. Fakhari Langroodi M, Gholami M, Shakeri N. The effect of eight weeks of Q10 supplementation combined with aerobic exercise on serum MDA, SOD and maximal oxygen consumption in women. Quarterly Journal of Breathing. 2020;5(1).
  16. 16. Feizi Y, Afzalpour M, Abtahi Avery S. The effect of short-term supplementation of coenzyme Q10 on malondialdehyde and serum catalase enzyme activity following moderate acute resistance exercise in inactive female students. Third International Conference on Applied Research in Physical Education, Sport Sciences and Championship 2018.
  17. 17. Armanfar M, Jafari A, Dehghan GR. Effect of coenzyme Q10 supplementation on exercise-induced response of oxidative stress and muscle damage indicators in male runners. Zahedan Journal of Research in Medical Sciences. 2015;17(8).
  18. 18. Chis BA, Chis AF, Muresan A, Fodor D. Q10 coenzyme supplementation can improve oxidative stress response to exercise in metabolic syndrome in rats. International journal for vitamin and nutrition research. 2019.
  19. 19. Alimohammadi M, Rahimi A, Faramarzi F, Golpour M, Jafari-Shakib R, Alizadeh-Navaei R, Rafiei A. Effects of coenzyme Q10 supplementation on inflammation, angiogenesis, and oxidative stress in breast cancer patients: a systematic review and meta-analysis of randomized controlled-trials. Inflammopharmacology. 2021;29(3):579-93.
  20. 20. Shen Q, Pierce JD, editors. Supplementation of coenzyme Q10 among patients with type 2 diabetes mellitus. Healthcare; 2015: MDPI.
  21. 21. Golpasasndi SH, Abdollahpour S, Golpasandi H. High-intensity interval training combined with saffron supplementation modulates stress-inflammatory markers in obese women with type 2 diabetes. Research in Exercise Nutrition 2022;1(1):55-61.
  22. 22. Suzuki K, Tominaga T, Ruhee RT, Ma S. Characterization and modulation of systemic inflammatory response to exhaustive exercise in relation to oxidative stress. Antioxidants. 2020;9(5):401.
  23. 23. Ighodaro O, Akinloye O. First line defence antioxidants-superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX): Their fundamental role in the entire antioxidant defence grid. Alexandria journal of medicine. 2018;54(4):287-93.
  24. 24. Surai PF. Antioxidant systems in poultry biology: superoxide dismutase. Journal of Animal Research and Nutrition. 2016;1(1):8.
  25. 25. Zor KR, Yılmaz U, Bozkurt SB. Coenzyme Q10 and Vitamin E Regulate the Bioactivity of Human Corneal Fibroblast Cells. Journal of Ocular Pharmacology and Therapeutics. 2024;40(8):494-503.
  26. 26. Singh Z, Karthigesu IP, Singh P, Rupinder K. Use of malondialdehyde as a biomarker for assessing oxidative stress in different disease pathologies: a review. Iranian Journal of Public Health. 2014;43(Supple 3):7-16.
  27. 27. Asgary S, Karimi R, Pour PM, Heydarpour F, Mostafaei S, Farzaei MH, et al. Is consumption of pomegranate supplementation effective on oxidative stress biomarkers including MDA, ox-LDL, POX 1, GPX, TAC, and TBRAS? A systematic review and meta-analysis of randomized controlled trials. Current problems in cardiology. 2023;48(8):101198.
  28. 28. Yang M-T, Lee X-X, Huang B-H, Chien L-H, Wang C-C, Chan K-H. Effects of two-week betaine supplementation on apoptosis, oxidative stress, and aerobic capacity after exhaustive endurance exercise. Antioxidants. 2020;9(12):1189.
  29. 29. Kendra J, Golpasandi SH, Naman A, Othman M, Kim J, Rauth R, et al., editors. Micronized Biocompatible Ceramic Promotes Muscle Derived IL-6 Release in Disuse. International Journal of Exercise Science: Conference Proceedings; 2024.
  30. 30. Biabani N, Taherpour K, Ghasemi HA, Akbari Gharaei M, Hafizi M, Nazaran MH. Advanced chelate technology-based trace minerals reduce inflammation and oxidative stress in Eimeria-infected broilers by modulating NF-kB and Nrf2 pathways. Scientific Reports. 2024;14(1):24227.
  31. 31. Nash D. The IL-6 signalling pathway: potential biomarkers for training load, performance, and health status in endurance runners? : Cardiff Metropolitan University; 2024.
  32. Drobnic F, Lizarraga MA, Caballero-García A, Cordova A. Coenzyme Q10 supplementation and its impact on exercise and sport performance in humans: a recovery or a performance-enhancing molecule? Nutrients. 2022;14(9):1811.

 

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