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The effect of exercise with an energy expenditure of 3000 kcal per week on hsCRP, MDA, and insulin resistance in overweight women | ||
| Research in Exercise Nutrition | ||
| دوره 4، شماره 1، خرداد 2025، صفحه 96-75 اصل مقاله (1.32 M) | ||
| نوع مقاله: Research Paper I Open Access I Released under (CC BY-NC 4.0) license | ||
| شناسه دیجیتال (DOI): 10.22034/ren.2025.143862.1108 | ||
| نویسندگان | ||
| Saeid Dabbagh Nikoukheslat* 1؛ Bahluol Ghorbaninan2؛ Nafiseh Rahnama Hayati3؛ Elaheh Piralaiy3؛ Mostafa Khani3 | ||
| 1Department of Exercise Physiology, Faculty of Physical Education and Sport Science, University of Tabriz, Tabriz, Iran. | ||
| 2Department of Sport Sciences, Faculty of Educational Sciences and Psychology, Azerbaijan Shahid Madani University , Tabriz, Iran. | ||
| 3Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Tabriz, Tabriz, Iran. | ||
| چکیده | ||
| Aim: Given the prevalence of overweight and the associated increase in oxidative stress as one of its major adverse consequences, the present study aimed to the effects of exercise with an energy expenditure of 3000 kcal per week on hsCRP, MDA, and insulin resistance in overweight women. Methods: This experimental study followed a pre-–post-test design and was conducted on 27 participants divided into three groups high-energy expenditure exercise (HCE), standard-energy expenditure exercise (SCE), and control (CON). The training program for the HCE group involved an energy expenditure of 1200 kcal (50–60% VO2max) in the first week and 3000 kcal (70–85% VO2max) in the final week. The SCE group with an energy expenditure of 900 kcal (65–75% VO2max) in the first week and 1200 kcal (70–85% VO2max) in the final week. MDA, hsCRP, insulin, and HOMA-IR were measured as indicators of oxidative stress, inflammation, and insulin resistance. Data analyzed using a 2×3 repeated-measures ANOVA at a significance level of P≤0.05. Results: The findings, a significant reduction in MDA levels was observed only in the SCE group across measurement phases (P=0.043).,a significant increase in hsCRP was found in the HCE group compared to the SCE (P=0.010) and CON (P=0.005) groups. No other significant differences were observed (P>0.05). Conclusion: Based on the results, combined training with an energy expenditure of 3000 kcal per week, compared to standard exercise protocols, did not result in significant increases in oxidative stress, systemic inflammation, or insulin dysfunction after 12 weeks., such high-energy training protocols can be considered metabolically and inflammatorily safe. | ||
| کلیدواژهها | ||
| High energy expenditure؛ exercise؛ hsCRP؛ Insulin resistance؛ MDA | ||
| مراجع | ||
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آمار تعداد مشاهده مقاله: 305 تعداد دریافت فایل اصل مقاله: 44 |
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