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The effect of selenium consumption on liver damage index during exercise in a hot environment in rats | ||
| Research in Exercise Nutrition | ||
| مقاله 5، دوره 5، شماره 1، خرداد 2026 | ||
| نوع مقاله: Research Paper I Open Access I Released under (CC BY-NC 4.0) license | ||
| شناسه دیجیتال (DOI): 10.22034/ren.2026.144855.1145 | ||
| نویسندگان | ||
| Marziyeh Gholami؛ Elham Vosadi* ؛ Adel Donyaei | ||
| Department of Exercise Physiology, Faculty of Physical Education and sport sciences, Shahrood University of Technology, Semnan, Iran. | ||
| چکیده | ||
| Aim: Exercise in a hot environment is associated with dysfunction of the liver. The purpose of this study was to investigate the effect of exercise in a hot environment combined with selenium consumption on liver indices in rats. Method: In this experimental study, 32 male Wistar rats were divided into four groups: control, exercise in a normal environment, exercise in a warm environment, and exercise in a warm environment with selenium supplementation. Exercise was performed for eight weeks in a normal and warm environment. Selenium was administered as an oral supplement at a specific dose. At the end of the period, liver tissue was sampled and ALT and AST gene expression were measured. After confirming the normal distribution of the data, one-way analysis of variance was used to compare the groups and, if necessary, Bonferroni's test was used. Results: AST gene expression showed a significant increase in the warm environment training groups compared to the control group and a significant decrease in the warm environment + selenium training group, while the difference between the control group and the normal environment training group was not significant. ALT gene expression showed a significant increase in the warm environment training group compared to the control. Also, the warm environment + selenium training group had a decrease in ALT gene expression compared to the warm environment training group. Conclusion: Training in a hot environment can lead to liver damage, but selenium supplementation plays an effective role in reducing these damages and improving physiological responses. | ||
| کلیدواژهها | ||
| Liver damage indices؛ selenium؛ exercise in hot environments | ||
| مراجع | ||
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آمار تعداد مشاهده مقاله: 51 |
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